B-cell differentiation pattern of cutaneous lymphomas in infancy and childhood
نویسندگان
چکیده
منابع مشابه
Cutaneous B-cell Lymphomas
Clinical features and history Cutaneous B-cell lymphomas usually present as one or more erythematous papules or nodules that may coalesce to form plaques. They are usually localized tumors effecting one cutaneous region and rarely ulcerate. There is some regional predilection for various sub-types of tumors; follicle center lymphoma more commonly arises on the scalp, marginal zone B-cell lympho...
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Among extranodal non-Hodgkin's lymphomas, primary cutaneous lymphomas (CLs) represent a consistent group of B- and T-cell malignancies. We investigated the arrangement of Ig and T-cell receptor (TCR) genes, together with the involvement of several oncogenes and the tumor-suppressor gene p53, in a panel of primary cutaneous B- and T-cell lymphomas (CBCLs and CTCLs). Southern blot analysis was pe...
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Aberrant expression of microRNAs is widely accepted to be pathogenetically involved in nodal diffuse large B-cell lymphomas (DLBCLs). However, the microRNAs profiles of primary cutaneous large B-cell lymphomas (PCLBCLs) are not yet described. Its two main subtypes, i.e., primary cutaneous diffuse large B-cell lymphoma, leg type (PCLBCL-LT) and primary cutaneous follicle center lymphoma (PCFCL) ...
متن کاملExpression pattern of XBP1(S) in human B-cell lymphomas.
The transcription factor XBP1 (X-box-binding protein 1) is essential for plasma cell (PC) differentiation and immunoglobulin secretion. XBP1 is widely expressed, but its activity is precisely controlled by mRNA splicing in response to endoplasmic reticulum (ER) stress. It is the active form of XBP1, XBP1(S), which is required for PC differentiation. The relationship between XBP1(S) expression a...
متن کاملChildhood B cell lymphomas arising in the mediastinum.
AIMS To report the clinical features and pathology of four childhood cases of primary mediastinal non-Hodgkin's lymphoma of non-lymphoblastic pathology. METHODS Biopsy material was fixed in formol-saline and routinely processed and stained. Immunohistochemical staining was performed on paraffin wax embedded sections using the alkaline phosphatase anti-alkaline phosphatase method. RESULTS Th...
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ژورنال
عنوان ژورنال: Cancer
سال: 1988
ISSN: 0008-543X,1097-0142
DOI: 10.1002/1097-0142(19880115)61:2<303::aid-cncr2820610220>3.0.co;2-3